AN ADVANCED COARSE-GRAINED NUCLEOSOME CORE PARTICLE MODEL FOR COMPUTER SIMULATIONS OF NUCLEOSOME-NUCLEOSOME INTERACTIONS UNDER VARYING IONIC CONDITIONS.

In the eukaryotic cell nucleus, DNA exists as chromatin, a compact but dynamic complex with histone proteins.The first level of DNA organization is the linear array of nucleosome core particles (NCPs).The NCP is a well-defined complex of 147 bp DNA with an octamer of histones.Interactions between NCPs are of paramount importance for higher levels o

This paper critically reviews and identifies gaps in the methodologies used to analyze the environmental impacts of mineral and metal global Blood Pressure Monitoring supply chains.Of specific focus are assessments of the extraction and production of minerals and metals needed for a low-carbon energy future.Current trends and projections suggest th

ABSTRACT Correlations between gene transcription and the abundance of high-energy purine nucleotides in Saccharomyces cerevisiae have often been noted.However, there has been no systematic investigation of this phenomenon in the absence of confounding factors such as nutrient status and growth rate, and there is little hard evidence for a causal re